Cotinine (COT) Rapid Test

Cotinine (COT) Rapid Test

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays.

In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.1 While cotinine is thought to be an inactive metabolite, it’s elimination profile is more stable than that of nicotine which is largely urine pH dependent. As a result, cotinine is considered a good biological marker for determining nicotine use.

Ordering Information

Product Description: Cotinine (COT) Rapid Test
Test Specimen: Urine, Oral Fluid, Powder, WB/S/P
Test Format: Dipstick,Cassette,Panel,Cup, Midstream
Test Pack: 25T,40T,50T

*Please refer to the “T&D Product Catalogue” for detailed ordering information,thanks.